The girls and staff all contribute to the life and worship in a variety of ways; serving, reading, Eucharistic ministry for the whole school Masses. Class and House Masses are also celebrated, giving the girls the opportunity for worship in a more informal setting. Pupils are encouraged to assist in planning and leading these services.

In both whole school and House assemblies, the girls often prepare and lead worship. This can range from reflecting on the life of a saint whose feast day the church is celebrating to a dramatic presentation of the teachings of the prophets. Staff too across the curriculum lead whole school prayers demonstrating the rich traditions and styles present in the St Mary's community.